CASE WESTERN RESERVE UNIVERSITY

$1,607,976

from Department of Health and Human Services · National Institutes of Health

MECHANISMS OF CMYBP-C MEDIATED FINE-TUNING OF CARDIAC CONTRACTILE FUNCTION - ABSTRACT COORDINATED INTERACTIONS BETWEEN THIN AND THICK FILAMENT PROTEINS FORM THE BASIS OF CARDIAC MUSCLE REGULATION. THE MYOSIN MOLECULE CAN EXIST IN DIFFERENT CONFORMATIONAL STATES ALONG THE THICK FILAMENT THAT FAVOR OR INHIBIT ACTIN BINDING AND FORCE GENERATION. SHIFTS IN THE EQUILIBRIUM OF MYOSIN CONFORMATIONS RE...
Description as recorded in the federal award record (cut at 400 characters).

Award ID: R01HL184474
Award type: PROJECT GRANT (B)
First obligated: Jul 14, 2026
Period starts: Jul 15, 2026
Place of performance: Cuyahoga County, Ohio 44106
Assistance listing: 93.837 CARDIOVASCULAR DISEASES RESEARCH
Amount means: Federal obligation for this grant, as of our last read Oct 13, 2026.

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