CASE WESTERN RESERVE UNIVERSITY

$635,545

from Department of Health and Human Services · National Institutes of Health

MITOCHONDRIAL MECHANISMS IN SYNUCLEINOPATHIES - PROJECT SUMMARY PARKINSON’S DISEASE (PD) AND DEMENTIA WITH LEWY BODIES (DLB) ARE PROGRESSIVE NEURODEGENERATIVE DISORDERS CHARACTERIZED BY PATHOLOGICAL Α-SYNUCLEIN (ΑSYN) ACCUMULATION, MITOCHONDRIAL DYSFUNCTION, AND CHRONIC NEUROINFLAMMATION. WHILE ΑSYN AGGREGATION IS A HALLMARK OF PD AND DLB, THE MOLECULAR MECHANISMS DRIVING ITS MISFOLDING AND TOX...
Description as recorded in the federal award record (cut at 400 characters).

Award ID: R01AG099057
Award type: PROJECT GRANT (B)
First obligated: Sep 4, 2026
Period starts: Sep 15, 2026
Place of performance: Cuyahoga County, Ohio 44106
Assistance listing: 93.866 AGING RESEARCH
Amount means: Federal obligation for this grant, as of our last read Oct 13, 2026.

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