CASE WESTERN RESERVE UNIVERSITY

$496,214

from Department of Health and Human Services · National Institutes of Health

REPURPOSING THE NMDA RECEPTOR ANTAGONIST MEMANTINE AS A COGNITIVE ENHANCER IN STAGE 0 ALZHEIMER'S DISEASE IN PERSONS WITH DOWN SYNDROME - ABSTRACT PERSONS WITH DOWN SYNDROME (DS) DEVELOP THE EARLIEST DOCUMENTED FORM OF ALZHEIMER'S DISEASE (AD)-TYPE PATHOLOGY. APPROXIMATELY 50% OF THOSE WITH DS MEET CLINICAL DEMENTIA DIAGNOSIS CRITERIA BY 55 YEARS OF AGE, AND IT IS ESTIMATED THAT PERSONS WITH DS...
Description as recorded in the federal award record (cut at 400 characters).

Award ID: UG3AG101220
Award type: COOPERATIVE AGREEMENT (B)
First obligated: Sep 7, 2026
Period starts: Sep 15, 2026
Place of performance: Cuyahoga County, Ohio 44106
Assistance listing: 93.310 TRANS-NIH RESEARCH SUPPORT
Amount means: Federal obligation for this grant, as of our last read Oct 13, 2026.

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