CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY

$413,339

from Department of Health and Human Services · National Institutes of Health

ALIGNING T-CELL BIOLOGY WITH CAR ARCHITECTURE TO ENHANCE LYMPHOMA THERAPY - PROJECT SUMMARY / ABSTRACT CHIMERIC ANTIGEN RECEPTOR (CAR) T-CELL THERAPY HAS REVOLUTIONIZED THE TREATMENT OF B-CELL MALIGNANCIES, YET DURABLE RESPONSES ARE ACHIEVED IN ONLY 35–50% OF LYMPHOMA PATIENTS. CLINICAL AND TRANSCRIPTOMIC COMPARISONS REVEAL THAT CD28Æ-BASED CARS EXPAND RAPIDLY, SHOW STRONG EARLY EFFICACY ASSOCI...
Description as recorded in the federal award record (cut at 400 characters).

Award ID: R01CA316454
Award type: PROJECT GRANT (B)
First obligated: Jul 31, 2026
Period starts: Aug 1, 2026
Place of performance: Cuyahoga County, Ohio 44195
Assistance listing: 93.395 CANCER TREATMENT RESEARCH
Amount means: Federal obligation for this grant, as of our last read Oct 13, 2026.

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