CASE WESTERN RESERVE UNIVERSITY

$393,812

from Department of Health and Human Services · National Institutes of Health

PHOTOBIOMODULATION-ENHANCED CAR-T CELL THERAPY - PROJECT SUMMARY/ABSTRACT CHIMERIC ANTIGEN RECEPTOR (CAR) T-CELL THERAPY HAS REVOLUTIONIZED TREATMENT FOR B-CELL CANCERS, ACHIEVING REMISSION IN OVER HALF OF PATIENTS. HOWEVER, ITS EFFECTIVENESS IS LIMITED BY SLOW, COSTLY MANUFACTURING THAT YIELDS TERMINALLY DIFFERENTIATED, EXHAUSTION-PRONE EFFECTOR CELLS, RESULTING IN POOR PERSISTENCE AND HIGH CO...
Description as recorded in the federal award record (cut at 400 characters).

Award ID: R21CA318125
Award type: PROJECT GRANT (B)
First obligated: Jul 31, 2026
Period starts: Aug 1, 2026
Place of performance: Cuyahoga County, Ohio 44106
Assistance listing: 93.395 CANCER TREATMENT RESEARCH
Amount means: Federal obligation for this grant, as of our last read Oct 13, 2026.

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