RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL

$616,577

from Department of Health and Human Services · National Institutes of Health

UNDERSTANDING PATHOLOGICAL MECHANISMS AND DEVELOPING NOVEL THERAPEUTIC APPROACHES FOR CMT1B DISEASE - PROJECT SUMMARY/ABSTRACT MUTATIONS IN THE MYELIN PROTEIN ZERO (MPZ) GENE CAUSE ONE OF THE MOST COMMON FORMS OF HEREDITARY NEUROPATHY KNOWN AS CHARCOT-MARIE-TOOTH TYPE 1B (CMT1B) DISEASE WITH PHENOTYPES RANGING FROM SEVERE EARLY-ONSET DEMYELINATING TO LATE-ONSET AXONAL NEUROPATHY. CMT1B IS A DEB...
Description as recorded in the federal award record (cut at 400 characters).

Award ID: R01NS146580
Award type: PROJECT GRANT (B)
First obligated: Aug 14, 2026
Period starts: Aug 14, 2026
Place of performance: Franklin County, Ohio 43205
Assistance listing: 93.853 EXTRAMURAL RESEARCH PROGRAMS IN THE NEUROSCIENCES AND NEUROLOGICAL DISORDERS
Amount means: Federal obligation for this grant, as of our last read Oct 13, 2026.

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