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Franklin County · Grant

OHIO STATE UNIVERSITY, THE

$521,858

from Department of Health and Human Services · National Institutes of Health

GRAPH-AI MODEL GUIDED TARGET AND SYNTHETIC LETHALITY DISCOVERY AMONG CELL-DEATH PATHWAYS - SUMMARY A GENE PAIR IS DEFINED AS SYNTHETIC LETHAL (SL) WHEN COMPROMISED FUNCTION OF BOTH GENES IN THE PAIR RESULTS IN CELL DEATH, BUT THE CELL SURVIVES WHEN THE FUNCTION OF ONLY ONE OF THE GENES IS LOST. WHILE CRISPR-CAS9 AND GENE COMBINATION DOUBLE KNOCKOUT (CDKO) EXPERIMENTS ARE BECOMING STANDARD APPRO...

Description as recorded in the federal award record (cut at 400 characters).
Award ID
R01GM162892
Award type
PROJECT GRANT (B)
First obligated
Sep 4, 2026
Period starts
Sep 4, 2026
Place of performance
Franklin County, Ohio 43210
Assistance listing
93.859 BIOMEDICAL RESEARCH AND RESEARCH TRAINING
Amount means
Federal obligation for this grant, as of our last read Oct 13, 2026.

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