RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL

$490,216

from Department of Health and Human Services · National Institutes of Health

TARGETING PURINE CATABOLISM AND SIGNALING IN T CELL AUTOIMMUNITY - SUMMARY: PROPERLY ALLOCATING METABOLIC RESOURCES IS CRUCIAL FOR SUPPORTING THE ENERGETICALLY DEMANDING PROCESSES OF T- CELL PROLIFERATION AND INFLAMMATION THAT DRIVE AUTOIMMUNE DISEASES, SUCH AS MULTIPLE SCLEROSIS AND RHEUMATOID ARTHRITIS. ADDITIONALLY, METABOLITES CAN ACT AS LIGANDS THAT INTERACT WITH SPECIFIC CELL-SURFACE RECE...
Description as recorded in the federal award record (cut at 400 characters).

Award ID: R37AI114581
Award type: PROJECT GRANT (B)
First obligated: Aug 31, 2026
Period starts: Aug 15, 2015
Place of performance: Franklin County, Ohio 43205
Assistance listing: 93.855 ALLERGY AND INFECTIOUS DISEASES RESEARCH
Amount means: Federal obligation for this grant, as of our last read Oct 13, 2026.

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