CHILDRENS HOSPITAL MEDICAL CENTER

$703,409

from Department of Health and Human Services · National Institutes of Health

ROLE OF CLIC/GEEC PATHWAY IN VCC FORMATION AND HIV-1 TRANSMISSION FROM MACROPHAGES - SUMMARY MYELOID CELLS CAPTURE FREE HIV-1 PARTICLES VIA INTERACTIONS BETWEEN CELL SURFACE SIGLEC-1 AND GANGLIOSIDES ON THE VIRAL LIPID ENVELOPE. FOLLOWING PARTICLE CAPTURE, THE SIGLEC-1-HIV-1 COMPLEXES COALESCE ON THE SURFACE AND THEN ARE TAKEN INTO A COMPLEX INTRACELLULAR COMPARTMENT TERMED THE VIRUS-CONTAINING...
Description as recorded in the federal award record (cut at 400 characters).

Award ID: R56AI197882
Award type: PROJECT GRANT (B)
First obligated: Aug 3, 2026
Period starts: Sep 1, 2026
Place of performance: Hamilton County, Ohio 45229
Assistance listing: 93.855 ALLERGY AND INFECTIOUS DISEASES RESEARCH
Amount means: Federal obligation for this grant, as of our last read Oct 13, 2026.

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