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Hamilton County · Grant

CHILDRENS HOSPITAL MEDICAL CENTER

$608,215

from Department of Health and Human Services · National Institutes of Health

IKEGAMI - R01 - NUCLEAR RUPTURE AND REPAIR IN LAMIN-ASSOCIATED CARDIOMYOPATHY - PROJECT SUMMARY LMNA-ASSOCIATED DILATED CARDIOMYOPATHY (LMNA-DCM) IS A FATAL GENETIC DISEASE, FOR WHICH HEART TRANSPLANTATION IS THE ONLY EFFECTIVE TREATMENT. IT IS CAUSED BY LOSS-OF-FUNCTION MUTATIONS IN LAMIN A/C (LMNA), A KEY NUCLEAR ENVELOPE PROTEIN. PROGRESS TOWARD THERAPY HAS BEEN BLOCKED BY THE LACK OF UNDERS...

Description as recorded in the federal award record (cut at 400 characters).
Award ID
R01HL187557
Award type
PROJECT GRANT (B)
First obligated
Sep 8, 2026
Period starts
Sep 5, 2026
Place of performance
Hamilton County, Ohio 45229
Assistance listing
93.837 CARDIOVASCULAR DISEASES RESEARCH
Amount means
Federal obligation for this grant, as of our last read Oct 13, 2026.

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