CHILDRENS HOSPITAL MEDICAL CENTER

$445,500

from Department of Health and Human Services · National Institutes of Health

TARGETING UNDRUGGABLE LUNG VASCULAR ENHANCERS WITH COMPACT AAV-CAS12F CRISPR ACTIVATION - PROJECT SUMMARY REGULATORY DNA ELEMENTS CONTROL CELL- AND TISSUE- SPECIFIC GENE EXPRESSION BUT HAVE TRADITIONALLY BEEN CONSIDERED UNDRUGGABLE DUE TO ABSENCE OF PRECISE TOOLS TO MODULATE THEIR ACTIVITY. TO ADDRESS THIS CHALLENGE, WE PROPOSE TO DEVELOP A COMPACT CRISPR-BASED MODULATION SYSTEM USING THE MINIA...
Description as recorded in the federal award record (cut at 400 characters).

Award ID: R21HD123012
Award type: PROJECT GRANT (B)
First obligated: Aug 19, 2026
Period starts: Sep 1, 2026
Place of performance: Hamilton County, Ohio 45229
Assistance listing: 93.865 CHILD HEALTH AND HUMAN DEVELOPMENT EXTRAMURAL RESEARCH
Amount means: Federal obligation for this grant, as of our last read Oct 13, 2026.

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