UNIVERSITY OF TOLEDO

$248,999

from Department of Health and Human Services · National Institutes of Health

INDUCED-PROXIMITY PLATFORM TO CONTROL CELLULAR SIGNALING AND PROTEOSTASIS - THE DEVELOPMENT OF SMALL-MOLECULE MEDICINES THAT INHIBIT DISEASE-CAUSING PROTEINS HAS FUNDAMENTALLY TRANS-FORMED MODERN HEALTHCARE. HOWEVER, CONVENTIONAL DRUGS REQUIRE BINDING TO SPECIFIC ACTIVE POCKETS TO BLOCK PRO-TEIN FUNCTION, A MECHANISM THAT LIMITS THEIR EFFICACY TO ONLY ABOUT 10–15% OF THE HUMAN PROTEOME. MOST DI...
Description as recorded in the federal award record (cut at 400 characters).

Award ID: R00GM159057
Award type: PROJECT GRANT (B)
First obligated: Aug 21, 2026
Period starts: Sep 1, 2025
Place of performance: Lucas County, Ohio 43606
Assistance listing: 93.859 BIOMEDICAL RESEARCH AND RESEARCH TRAINING
Amount means: Federal obligation for this grant, as of our last read Oct 13, 2026.

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